The New Architecture for Therapeutics
Vector.
Vector.

Pipeline

3D molecular model of the complex formed between anti-CD19 scFv expressed from a circular RNA (Blue), and its target CD19 (Green)

Gradient Color
Left Gradient
Vector

PIPELINE

Programs advancing alongside continued platform innovation

Circurna is advancing a focused pipeline selected to enable early clinical validation of the platform while supporting long-term expansion into high-value therapeutic areas.

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2026
2027
2028
TAM
Program
Yellow Fever Vaccine Disease
2026
2027
2028
IND Filing
Safety PoC and
potential out-licensing
TAM
5.0B
Program
Melanoma Vaccine Oncology
2026
2027
2028
Candidate Selection
TAM
10.3B
Program
CD19 / CD20 CAR-T
Oncology / Autoimmune
2026
2027
2028
Candidate Selection
IND Filing
TAM
16.5B
Program
Solid tumor CAR-T Undisclosed Target Oncology
2026
2027
2028
Candidate Selection
TAM
12.0B
Program
Undisclosed Target
Fibrosis
2026
2027
2028
Candidate Selection
IND Filing
TAM
5.0B
Discovery
IND-Enabling
Phase 1

Notably shorter time to advance drug candidates into clinical trials

Focus Areas:

Intradermal Delivery
Oncology 
Fibrosis